Anti-fibrotic drugs mainly include Nidanib, Pirfenidone and so on.
1.Nidanib:belongs to the small molecule tyrosine kinase inhibitor, has the anti-fibrosis as well as anti-inflammatory activity, is mainly used for the treatment of idiopathic pulmonary fibrosis and other diseases. Thrombocytopenia, weight loss, loss of appetite may occur after the use of the drug, allergic to the components of the drug, liver injury is prohibited.
Diarrhea, nausea, vomiting, liver function abnormalities may occur during the use of the drug, and special groups such as pregnant women and lactating women, need to use the drug under the guidance of a doctor.
2. Pirfenidone: can inhibit cell proliferation caused by cell growth factor stimulation of fibroblasts, so it has anti-fibrotic and anti-inflammatory effects, mainly used for mild, moderate idiopathic pulmonary fibrosis and other diseases treatment. Liver function impairment, facial swelling, and breathing difficulties may occur with the use of this drug.
It is contraindicated for those who are allergic to the components of the drug, those with severe liver disease, and those with severe kidney disease. Regular monitoring of liver and kidney functions is required during the use of the drug, while special groups such as the elderly and children need to use the drug under the supervision of a doctor.
The above medication is recommended to be used under the guidance of a doctor to avoid adverse reactions from self-medication.