Enameloblastoma is a relatively common tumor of the oral and maxillofacial region, with a nature between benign and malignant tumors, mostly occurring in adults, with no significant difference in incidence between men and women, and more common in the mandible than the maxilla. There are different opinions about the cause of enameloblastoma, but all agree that it is a congenital developmental disease. The disease occurs most often in young adults, with the mandibular body and mandibular angle being the most common. It grows slowly and has no obvious symptoms at the beginning; gradually it can cause the jaw bone to expand, resulting in deformity and left and right facial asymmetry. If the tumor invades the alveolar process, it may lead to loosening and loss of teeth. When the tumor invades the inferior alveolar nerve, numbness and discomfort in the lower lip and cheek may also occur. For the treatment of enameloblastoma, there are three main treatment methods: 1. For cystic lesions, we mainly use open window surgery and wear a plugging device after surgery to make the tumor slowly regress; 2. For smaller tumors, we can use scraping or bone square resection; 3. For substantial or multi-cystic tumors, segmental bone resection is usually required, and bone defects can be repaired by bone grafting at the same time or in the second stage.