This patient was a 53-year-old female with a preoperative diagnosis of left kidney cancer. The imaging examination showed that the tumor resembled the size of a child’s head (14 cm in diameter) and the normal tissue structure of the affected kidney was completely destroyed. Due to the huge size, the tumor had significantly pushed and displaced the surrounding organs and was closely adherent, making surgical resection extremely difficult. After more than 4 hours of hard work, this “bomb” was finally removed from the patient’s body as a whole. The postoperative pathology report was clear cell carcinoma of the kidney, with complete resection and no cancerous tissue left at the edge. Soon after the operation, the patient recovered and was discharged from the hospital and is now regularly followed up in our urology department. The patient was found to have a standing left kidney lesion three years ago, but she gave up the best time for surgery at that time due to many factors. Fortunately, the preoperative examination did not reveal any distant organ metastasis, and a limited surgery to remove the tumor was the only ray of hope for cure. However, the risk of receiving a major surgical blow was equally fatal as the body was already quite thin due to the long suffering from the disease. That’s why the success of curing such patients is also a test of a hospital’s comprehensive strength. It is understood that the overall strength of the hospital is high to carry out such a difficult surgery, which requires not only a high level of urology professional medical team, but also the cooperation of the surgical intensive care unit, oncology, anesthesiology, operating room and other related departments. The successful cure of this patient once again proves that our department has considerable strength in comprehensive medical level.