Depression is mainly caused by unrestrained qi and emotional discomfort. It is mainly characterized by emotional disturbance, depression, boredom in the heart, fullness in the chest, obstruction in the throat, anger and crying. In Chinese medicine, there is a distinction between the broad sense and the narrow sense. The broad sense of depression is due to the dysfunction of the internal organs caused by external sensation, diet, or internal injury, resulting in unfavorable qi flow. In the narrow sense, it refers to depression caused by emotional discomfort. In Western medicine, depression, anxiety, and hysteria all belong to the category of depression in Chinese medicine. The human body in response to various external stimuli, moderate venting, is a normal state, conducive to the harmonization of qi and blood. If the emotions are too intense or persistently unresolved, it will cause the internal organs to become dysregulated, which will result in liver qi stagnation. The occurrence of depression is caused by the stagnation of liver qi. Liver qi stagnation can lead to liver depression and fire, and liver qi stagnation can occur. The initial stage of depression evidence belongs to the state of actual evidence, which can affect the heart, spleen and kidney over time, resulting in deficiency of the heart and spleen, loss of nourishment of the heart and mind, and deficiency of heart and kidney yin symptoms. Therefore, the clinical treatment should take into account the specific conditions of each individual.