Drinking coffee in moderation is generally not harmful to the human body, but drinking coffee in excess is harmful to the human body, may cause vegetative nerve disorders, affecting gastritis, peptic ulcer recovery. 1. Phytoneurological disorders: Excessive drinking of coffee causes an increase in nerve excitability, leading to insomnia, irritability, anxiety and thus inducing phytoneurological disorders. 2. Gastritis: coffee on the gastric mucosa will cause stimulation, gastritis patients drink coffee on the gastric mucosal damage, especially drinking coffee on an empty stomach, may aggravate the condition and lead to nausea, acid reflux, bloating and other discomforts, is not conducive to the recovery of the disease. 3. Peptic ulcer: peptic ulcer patients drink coffee on the gastric mucous membrane stimulation, causing acid reflux, heartburn, stomach pain, bloating and other discomforts, may aggravate the condition. Ordinary people usually do not recommend drinking more coffee, gastritis peptic ulcer patients can not drink coffee.