Stomach cancer has been one of the common malignant tumors in China, and the incidence rate is the highest among digestive system tumors. Compared with Europeans and Americans, Chinese people have a higher chance of stomach injury and are more likely to be targeted by stomach cancer. However, gastric cancer is preventable and treatable. As long as it is detected and treated early, the cure rate can reach 90%. 1.Is there any ethnic, geographical and age differences in stomach cancer? The Global Cancer Report 2014 released by the World Health Organization shows that there are 405,000 new cases of stomach cancer in China, accounting for 42.5% of the new cases in the world. In fact, the ethnic and geographic differences of stomach cancer are more obvious. East Asia is a high incidence area for gastric cancer, and the total number of gastric cancer cases in three countries, China, Japan and Korea, accounts for about 70% of the world. This is related to the genetic predisposition of the people in the region, the high consumption of barbecued and pickled foods in the diet, and the high rate of smoking. Specifically in mainland China, stomach cancer also “favors” people in coastal areas, the middle and lower reaches of the Yangtze River or relatively poor areas such as Jiangsu, Shandong, Anhui, Henan, Gansu, Inner Mongolia and Northeastern provinces who prefer high salt diets. In terms of age, the average age of onset of stomach cancer is 58 or 59 years old, but patients range from a few years old to over 90 years old. The youngest patient I encountered was only 9 years old, and the exact cause of the disease is unknown. In the past 10 years, the incidence of gastric cancer in China is in a generally stable and slightly increasing state. It should be noted that the incidence rate of young people is increasing faster than the national level, and most of them belong to diffuse gastric cancer, which is relatively more difficult to treat. 2.Does gastric cancer have precancerous lesions? What are the main symptoms? Gastric polyps, chronic atrophic gastritis and remnant stomach are the high-risk factors for gastric cancer. The occurrence of gastric cancer is a multi-factor, multi-level and multi-stage development process. In early stage, patients with gastric cancer often have no obvious symptoms, or only epigastric discomfort, atypical epigastric pain, loss of appetite, fullness, belching, and a few may have black stool or vomiting blood. Once the symptoms are more obvious, it often indicates that the gastric cancer has entered into the middle and late stage, which mainly manifests as: unexplained gradual wasting, anemia, hypoproteinemia, swelling, persistent epigastric pain, vomiting blood and black stool, etc. 3.What are the high-risk groups of gastric cancer? How to detect it at an early stage? ①People with family history of tumor. Among relatives in two or three generations who have had digestive system tumor or other tumors, their chances of getting stomach cancer will be higher. The response is to do professional tumor screening about 10 years earlier than the youngest age of cancer members in the family, and gastroscopy should be done for stomach cancer, every 3 years, according to the doctor’s recommendation. For example, if the minimum age of cancer members in the family is 55 years old, then the first gastroscopy should be done at the age of 40. ② are those who have bad habits such as long-term smoking, drinking alcohol, and especially love to eat hot food, pickled and barbecued food, and high-salt food. These habits can cause more serious damage to the stomach and should be adjusted in time. ③ are patients who have gastric diseases such as gastric ulcer and chronic gastritis. People with these diseases should be actively treated to prevent the disease from progressing and go to the hospital for regular review. 4.Will I get stomach cancer if I have chronic gastritis, gastric ulcer and other diseases? Some gastric diseases are high-risk factors for stomach cancer and need to be taken seriously, but having gastric diseases does not necessarily mean that you will get stomach cancer. Gastric ulcer is clearly associated with gastric cancer and can increase the risk of developing cancer. Long-term, severe chronic gastritis, such as those with atrophic changes, intestinal hyperplasia or atypical hyperplasia, must be closely monitored. In life, promptly say goodbye to bad habits, quit smoking and limit alcohol, and eat less fried and high-salt food, etc. In addition, it is important to see a gastroenterologist regularly every year, who will give specific advice on gastroscopy, medication, etc., depending on the situation.