Positive urine occult blood should be based on the actual situation to decide whether to perform a renal puncture biopsy, not a generalization. Urine occult blood refers to increased red blood cells in the urine, when the urine red blood cells >3 / HP, known as hematuria; in addition to the contamination of female menstrual blood, the feasibility of urinary erythrocyte morphology examination, to clarify whether the glomerular origin of hematuria. If the glomerulonephritic hematuria, and there is no urinary protein in the urine, indicating that it may just be an isolated hematuria, in this case, generally can not do renal biopsy, need to be regularly reviewed. However, if the patient is combined with positive proteinuria, 24-hour proteinuria > 1g, or combined with unexplained elevated blood creatinine, renal biopsy can be performed to clarify the type of pathology and assist in diagnosis and treatment. When you find positive urinary occult blood, you should consult the regular hospital in time, further examination under the guidance of the doctor, and if necessary, perform renal puncture biopsy to clarify the diagnosis.