Severe sweating is an abnormal increase in sweating, called hyperhidrosis, which includes generalized hyperhidrosis and restrictive hyperhidrosis. The activity of sweat glands is controlled by sympathetic nerves, mainly cholinergic fibers. Emotional changes, internal and external temperature changes, medications, and diet can affect the secretion of sweat glands. Hyperhidrosis is usually classified into two categories according to its pathogenesis: neurological hyperhidrosis and non-neurological hyperhidrosis. Systemic hyperhidrosis is often caused by febrile diseases, tropical environments, endocrine disorders, and neurological disorders. In hyperhidrosis caused by systemic diseases or endocrine disorders or medications, patients should actively treat the disease. Hyperhidrosis will improve after removing the cause, and appropriate oral sedatives or anticholinergic medications can be taken to relieve systemic hyperhidrosis. Patients with localized hyperhidrosis remove hyperhidrosis by diligent bathing, diligent changing of underwear and underwear, local topical application of antibacterial ointment or topical application of drugs that inhibit sweat gland secretion, and local Botox injections.