If it is transient hypothyroidism, it can usually be cured and will not cause significant impact on life. If it is permanent hypothyroidism, it is necessary to take levothyroxine and other drugs for long-term replacement therapy. Usually, the prognosis is good, but a few patients whose conditions are difficult to control may experience organ failure, mucous edema coma and other adverse consequences. 1. Transient hypothyroidism: such as gestational hypothyroidism, hypothyroidism of subacute thyroiditis, neonatal hypothyroidism, drug-induced hypothyroidism, iodine-deficiency hypothyroidism, etc., which usually can be recovered, with no obvious after-effects, and will not affect the quality of life. 2. Permanent hypothyroidism: such as post-thyroid surgery, congenital thyroid deficiency, Hashimoto’s thyroiditis, etc., which requires lifelong medication, such as levothyroxine, and can usually control the condition better. However, if the treatment is not timely or the patient’s underlying condition is poor, complications such as organ failure and mucous edema coma may occur. Patients with hypothyroidism are advised to seek prompt medical attention, active treatment and regular review.