The brain tissue will not be easily attacked by the outside world only when the skull is intact, but in daily life, the problem of skull defect is not uncommon. Skull defect is a health crisis, and the consequences are even more serious if it is not repaired in time. Therefore, when faced with the disorder of cranial defects, what patients should do is to go to the hospital for cranial repair surgery to restore the integrity of the cranial cavity before it is too late. Once the skull is damaged, the intracranial pressure will become unstable, the cerebrospinal fluid and blood circulation will be impaired, and the neurological function of the brain will be damaged, which will cause a series of skull defect syndrome. Cranial defects are dangerous and cranial repair surgery is imperative. Cranial repair surgery is a routine procedure that can be performed in many local hospitals, but the key is how well it works. Because most hospitals widely use titanium mesh material, the progressive nature of this material cannot be denied, but it also has many disadvantages and there may still be some post-operative problems. For example, infections and rejection reactions, cutting pain, material exposure, and interference with postoperative CT MRI. The PEEK material is a new type of polymer material that is highly compatible with titanium mesh and has no rejection reactions. PEEK is the ideal choice for cranial repair surgery. The price of peek, a cranial bone repair material, is what it is, and patients are more concerned about the price of PEEK. In fact, this is no definite value, because each patient’s skull defect size is different, the larger the area will require more material, the higher the cost, need to be assessed and judged according to the specific situation.