Acid reflux in the stomach in the middle of the night choking wake up, usually due to reflux esophagitis, peptic ulcer, it is recommended to promptly check, clear diagnosis, the corresponding treatment. Common causes and treatments 1, reflux esophagitis: due to relaxation of the lower esophageal sphincter, peristaltic decline in the esophageal wall, resulting in the reflux of stomach and duodenal contents into the esophagus, causing acid reflux, abdominal pain, burning sensation and blockage. Gastric motility drugs, such as domperidone and etopride, can be used as prescribed by the doctor or combined with proton pump inhibitors to reduce gastric acid and protease secretion; 2. Peptic ulcer: pain, acid reflux, heartburn, and vomiting can occur. Gastroscopy needs to be improved, along with adequate acid suppression therapy and strengthening of mucosal protective agents, such as omeprazole, magnesium aluminum carbonate, etc. Caution: Pay attention to the regular diet, do not overeat, eat regularly and quantitatively, chew slowly, eat less and more often, do not eat cold, spicy and stimulating food, eat less greasy food and sweets, and do not eat too much before bedtime. Usually eat more fresh vegetables, fruits, can be supplemented with a variety of vitamins, not only conducive to nutrient absorption, but also to speed up the emptying of the stomach.