The scrotum is usually not infertile after rubbing with alcohol. Male infertility is usually caused by congenital developmental abnormalities and endocrine dysfunction. Alcohol wiping of the scrotum usually does not cause infertility. Male reproductive function is usually determined by male testicular function, and the scrotal skin is tender, so alcohol wiping may produce irritation, but it will not affect infertility. Male infertility is usually caused by congenital developmental abnormalities and endocrine dysfunction. Abnormalities in male penile development such as micropenis and ectopic penis can lead to infertility, and abnormalities in testicular development such as cryptorchidism and ectopic testes can also lead to infertility. Endocrine disorders are caused by hormonal imbalance in the body, which affects the secretion of sex hormones and leads to infertility in men. Patients who are not feeling well need to consult a doctor for timely examination and early treatment.