Nexium generic name is esomeprazole, and ordinary omeprazole mainly in the price, efficacy differences. 1. Price: esomeprazole is an imported drug, the current specifications are 20mg/tablet and 40mg/tablet, usually 20mg/tablet price at 10 yuan/tablet, 40mg/tablet price is usually at 13 yuan/tablet. And ordinary omeprazole is usually 20mg/tablet, the price is cheaper, usually in the range of 0.2 yuan/tablet to 3 yuan/tablet. 2. Efficacy: because of the esomeprazole for the dextrose, in the acid suppression effect than ordinary omeprazole effect is better, usually oral 1 capsule in 24 hours have to achieve the effect of acid suppression, and ordinary omeprazole acid suppression effect is less than 12 hours.