Dermatomyositis may be related to the environment, immune disorders and other factors, and its treatment includes glucocorticosteroids, immunosuppressants, small molecule targeted drugs and so on.
1. Glucocorticoid: it is the basic drug for treating dermatomyositis, such as prednisone, etc. It may produce gastrointestinal discomforts, blood pressure and blood sugar abnormalities, osteoporosis, full-moon face, buffalo back and other adverse reactions, and it is also necessary to closely observe the infection situation during use to prevent infection. Active peptic ulcer, severe hypertension and hyperglycemia, serious infections are contraindicated.
2. Immunosuppressive drugs: including methotrexate, azathioprine, cyclosporine, tacrolimus, cyclophosphamide, etc., which may produce myelosuppression, hematopoiesis, liver and kidney function abnormalities and other adverse reactions. Allergy to the above drugs, severe immunosuppression, severe liver and kidney function abnormalities are strictly prohibited.
3. Small molecule targeted drugs: for the treatment of conventional hormones combined with traditional immunosuppressant therapy is not effective, you can consider the use of small molecule targeted drugs, such as baricitinib, tofacitinib and so on. May produce rash, local itching, redness and swelling and other adverse reactions, allergy to the drug, active infection, severe heart failure, malignant tumors are strictly prohibited.
Dermatomyositis patients can go to the rheumatology and immunology department of regular hospitals and other related departments for detailed consultation. The medication should be used in accordance with the doctor’s instructions, do not self-medication.