Blood sugar can not come down, it may be too short a period of time for hypoglycemic treatment has not yet produced a significant effect, but also may be caused by diet, exercise, medication, disease and other reasons. 1. Too short a period of hypoglycemic treatment: regular hypoglycemic treatment requires a certain period of time to be effective, especially for patients with more serious conditions at the onset of the disease, who need to adhere to the treatment. 2. Dietary factors: diabetic patients should adhere to a low-fat, low-sugar, low-salt diet, balanced nutrition, small meals, choose boiled, steamed and other healthy cooking methods. 3. Exercise factor: some patients’ activities are too small, the metabolism of glucose in the body is slower, which will also lead to blood glucose can not be lowered, it is recommended that appropriate exercise within the tolerable range, such as jogging, swimming, playing ball games, and so on. 4. Drug factors: If the glucose-lowering drugs do not work for a long time or are difficult to tolerate, you can adjust the medication under the guidance of a doctor. 5. Disease factors: If diabetic patients suffer from other diseases, such as Cushing’s syndrome, adrenocortical hyperplasia, etc., may also lead to long-term difficulty in lowering blood glucose, and can improve the relevant examination to confirm the diagnosis. It is recommended that diabetic patients seek medical attention in a timely manner.