Itchy blisters on the hands may be caused by sweating herpes, papular urticaria, ringworm and other diseases. It can be used externally to stop itching, glucocorticoids, antifungal and other drugs. If necessary, with oral antihistamine drugs for treatment, can promote recovery. 1. Sweat herpes: it is easy to occur in the hot summer, related to poor sweating, resulting in the appearance of small transparent blisters on the hands, accompanied by itching and peeling. It can be applied topically with topical Dinaid cream and urea Vitamin E cream. If the itching is severe, if necessary, with olopatadine hydrochloride tablets, loratadine tablets anti-allergy treatment. 2. Papular urticaria: not pay attention to skin protection, by mosquito bites, resulting in localized pimples, papules with itching. You can use glycerine lotion, mometasone furoate ointment to apply externally. If necessary, oral fexofenadine, levocetirizine and other drugs. 3. Ringworm: Fungal infection causes ringworm, resulting in localized blisters and itching. If the examination determines that it is fungus positive, you can apply ketoconazole and miconazole nitrate ointment externally. If necessary, oral itraconazole capsules, and other antifungal drug treatment. It is recommended to pay attention to the cleanliness and hygiene of the hands, go to the hospital dermatology department to find the cause, and follow the doctor’s instructions to standardize the treatment.