The harm of high jaundice in newborns needs to be based on the specific situation. If it is physiological jaundice, it can generally subside by itself without much harm; if it is pathological jaundice, it may cause bilirubin encephalopathy, auditory developmental disorders, liver damage, neurological abnormality and so on, and the specific analysis is as follows: 1. Bilirubin encephalopathy: when the jaundice of newborn babies is too high, bilirubin may enter the brain, which not only produces certain damage to the brain nerves, but also causes bilirubin encephalopathy and affects the development of the brain. 2. Hearing development disorder: excessive jaundice may also affect the baby’s sense of hearing, causing hearing development disorder. 3. Liver damage, neurological abnormalities: Jaundice is a symptom that can be caused by other diseases, such as cytomegalovirus infection, which can cause liver damage and neurological abnormalities. High jaundice may also have other harmful effects. It is recommended that newborns with jaundice should seek medical treatment in time.