IOLs are biocompatible and generally last a lifetime after implantation in the eye, but if complications such as lens ectasia or endophthalmitis occur, the lens will need to be removed. IOLs are categorized differently depending on the material, the position in which they are placed, the functional classification, and the size of the surgical incision. Regardless of the type of IOL, generally speaking, if there is no displacement, dislocation, trauma, clouding, or rupture of the IOL, it can be maintained for the rest of one’s life without the need for surgical replacement. However, a small number of people may experience clouding of the IOL, which is extremely rare and may be related to the material of the IOL or changes in the intraocular environment. In this case, it is necessary to remove the cloudy IOL and implant another IOL. It is recommended that patients who experience discomfort after IOL implantation should consult a doctor in a timely manner to have their condition evaluated and to follow the doctor’s instructions for treatment.