Leg pain on Anrotinib hydrochloride is not necessarily caused by taking this medication and other factors need to be considered. Common side effects of taking Anrotinib hydrochloride are high blood pressure, fatigue, proteinuria, and skin reactions in the hands and feet. Some people may also experience allergic reactions, which are characterized by itchy skin, red eyes, and rashes. In addition to this, some patients may also experience adverse reactions such as elevated aminotransferases, fatigue, loss of appetite, and vomiting. Generally, there is no adverse reaction of leg pain. Leg pain can also be caused by wind-cold, bruises, rheumatism, rheumatoid rheumatism, calcium deficiency and other causes. Patients taking Anrotinib Hydrochloride for leg pain need to actively consult a doctor, to treat the symptoms, but also for the cause of the treatment, to avoid delays in the condition, not unauthorized medication.