Pain in the biting muscle area of the right cheek and inability to open the mouth may be due to wisdom tooth pericoronitis, acute periapical inflammation, biting muscle spasm and other reasons. 1. Wisdom tooth pericoronitis: If you suffer from wisdom tooth pericoronitis, the inflammation of wisdom tooth may lead to the infection of the occlusal space or maxillary space, which may result in the symptoms of pain in the occlusal area of the right cheek and inability to open the mouth, swollen gums, and so on, which can be treated with medicines such as amoxicillin and ibuprofen under the guidance of the doctor. 2. Acute periapical inflammation: If you suffer from acute periapical inflammation, there may be pain in the biting muscle area of the right cheek, inability to open the mouth, accompanied by fever, discomfort and other systemic symptoms, you can use metronidazole, dexamethasone and other medications under the guidance of the doctor’s instructions. 3.. Bite muscle spasm: if you suffer from bite muscle spasm, may be due to mental stress, calcium nutritional insufficiency, there may be a right cheek bite muscle area pain can’t open the mouth, can be in the doctor’s instructions under the guidance of the use of carbamazepine, clonazepam and other drugs. The right cheek biting muscle area pain can not open the mouth, we should go to the hospital in a timely manner, to clarify the cause of the disease, under the guidance of the doctor active treatment, the use of drugs need to follow the doctor’s instructions.