A gestational sac of 2.2 centimeters without a fetal heartbeat is not normal and should be combined with laboratory tests to assist in diagnosis and treatment. Women who are preparing for pregnancy can usually see the embryonic buds and fetal heartbeat when they undergo ultrasound at about 6 weeks after menopause, and they can also check the gestational week by the size of the gestational sac and the embryonic buds. When the ultrasound indicates a 2.2 cm gestational sac, the gestational week is roughly 7 weeks. The absence of a fetal heartbeat at this time is not normal and can be diagnosed by combining progesterone, estradiol, and HCG (human chorionic gonadotropin) levels. When the laboratory indicators are low, progesterone, low molecular heparin and other drugs can be given as prescribed by the doctor to actively treat the pregnancy, and after 7 to 10 days of treatment, the ultrasound and progesterone, HCG and estradiol levels can be rechecked, when the ultrasound suggests that the embryo is growing and the fetal heart can be seen, and the laboratory indicators are elevated, then the treatment can be continued under observation, but the pregnancy can be terminated in time according to the doctor’s advice when the fetal heart is not yet seen. When the ultrasound examination shows that the gestational sac is 2.2 centimeters and there is no fetal heart, appropriate treatment can be given under the guidance of the doctor, and the examination can be repeated on a regular basis.