Interferon in a 1°C refrigerator can be used if stored properly and within the shelf life. Interferon should be stored at 2 to 8°C. In a 1°C refrigerator, interferon can be used normally as long as it is not frozen, has not been subjected to freezing, and is within its shelf life. However, the drug should be used in accordance with medical advice. Interferon should also be stored in a way that avoids violent shaking and direct sunlight. After the injection of interferon, there will be fever, leukopenia and other adverse reactions, can be given fever and other symptomatic treatment. In the course of use, white blood cell and platelet counts should be monitored regularly under the guidance of specialized physicians, and once obvious abnormalities occur, medical consultation should be sought promptly for treatment.