If there is only one testicle, a physical examination is recommended to rule out the presence of cryptorchidism or testicular dislocation in the patient. If various surgeries result in unilateral testicle removal and only one testicle is left, the possible effects: 1. Difficulty in conception due to insufficient semen count. Because the testicle is a bilateral symmetrical organ, both can produce sperm. If the sperm production function of the opposite side is insufficient after unilateral absence, the number of sperm may decrease. 2. There is a vascular network connecting the testes, and if harmful substances are transferred to the normal side of the testes through the connecting network due to inflammatory disease or reversal of necrotic disease on one side, it may affect the normal side of the testes, affecting the epithelium of the normal side of the testes and causing sperm disorder and decrease in number. 3. If there is no fertility requirement, there may be no significant change in the quality of life. However, there may be insufficient androgen secretion, which may lead to anemia, osteoporosis, and weakness.