cd4 refers to CD4⁺T cells, CD4⁺T cell absolute count is low need to find the cause of the disease, for the cause of the active treatment, such as the use of antiviral drugs, immunomodulators and so on. CD4⁺T cells are a very important type of immune cells in the human immune system, and low absolute CD4⁺T cell counts can be seen in patients with AIDS because HIV mainly attacks CD4⁺T cells, which destroys the human immune system and makes the patient prone to opportunistic infections. Infections. Low absolute CD4⁺ T-cell counts can also be caused by autoimmune diseases, such as systemic lupus erythematosus, as well as hematologic diseases, such as aplastic anemia and infectious mononucleosis. These diseases cause a mild decrease in CD4⁺T cell counts. When the absolute CD4⁺T cell count is low, appropriate treatment is needed to address the cause. In the case of AIDS patients, long-term antiviral therapy under the supervision of a doctor is needed, using antiviral drugs such as lamivudine, abacavir, tenofovir, etc. In autoimmune diseases and hematologic diseases, active treatment of the primary disease and control of the course of the primary disease, as well as the use of whitening drugs, immunomodulators, etc., can promote the elevation of CD4 ⁺ T-cells and restore the immune function.