”Cough, cough, cough”, a violent dry cough woke me up from my sleep, it was my wife coughing. Why was she coughing again? My wife was diagnosed with bronchial asthma last winter. According to the treatment guidelines for bronchial asthma, I gave her terbutaline sulfate and budesonide inhalation treatment. The former drug is a bronchodilator and the latter is a glucocorticoid with anti-inflammatory effects, etc. After using them, the effect was really good. After using it, it worked really well and the cough improved significantly. After two weeks, I asked her to stop the terbutaline sulfate and the cough did not appear. 3 months later, I asked her to gradually stop the budesonide as well. But half a month later, the cough came back. It seemed that this budesonide could not be stopped, so I had to repeat the previous course of treatment again. I hardly saw my wife coughing for the past six months. However, tonight’s cough was really strange. She hasn’t had a cold lately, has she? Did she stop taking budesonide again? I suddenly remembered that a month ago, my wife asked me if budesonide was hormonal. Is she afraid of hormones …… Under my questioning, my wife said aggressively, “I did stop using it because this medicine is hormonal! I saw a lot of content in the medical book in your cabinet about the adverse effects of hormones, what ‘full moon face’, ‘buffalo back’ ah, really scared to death! I don’t need hormones even if I die of coughing.” When I heard that, I was speechless. It seems that the problem is still with me. As a doctor, I usually explain clearly to my patients the effects and adverse reactions of these drugs, but to my own wife, I neglected. It seemed that I had to make up for this lesson. I didn’t care that it was already late at night, so I got up and gave my wife a serious talk about the relationship between hormones and bronchial asthma. Bronchial asthma is a “chronic inflammation of the respiratory tract”. This inflammation is not the “inflammation” that we usually think of as being caused by a bacterial infection, but an “inflammation” related to the body’s autoimmunity. This “chronic inflammation of the respiratory tract” can cause spasms in the trachea and bronchi, causing symptoms such as coughing and shortness of breath. If repeated, it can have a negative impact on respiratory function, such as emphysema. Glucocorticosteroids are the most effective drugs to fight this inflammation. Most patients with bronchial asthma require inhaled hormones. Long-term inhalation of small doses of glucocorticosteroids can prevent asthma attacks. Indeed, traditional glucocorticosteroids, such as dexamethasone, can cause a series of adverse effects, such as “centripetal obesity” and “hyperglycemia,” when given orally, intramuscularly or intravenously over a long period of time. Fortunately, bronchial asthma is an inflammatory disease that occurs in the respiratory tract and can be treated by inhaling the medication directly into the airways. This greatly reduces the adverse effects of systemic medication. Moreover, budesonide is a new type of glucocorticoid, which has fewer adverse effects, strong local therapeutic effects, and is safe for long-term inhalation treatment, even for children. So, what should we pay attention to with the medication? 1, to do the correct use of inhalation apparatus. If you do not know how to use the inhalation apparatus, you can consult a respiratory doctor. 2.To rinse your mouth after using the medication to prevent the drug from remaining in the throat and thus producing adverse reactions. 3.Visit the respiratory clinic regularly to adjust the dosage of medication according to your condition. After listening to my words, my wife blamed me for not telling her earlier. From then on, my wife insisted on using the medication.