Different people react differently to medications, so there is no standard answer to which is better, vardenafil or sildenafil. The choice needs to be based on the patient’s specific situation. Vardenafil and sildenafil are both drugs used to treat male dysfunction, and both belong to the PDE5 inhibitors, but the drugs themselves will have some differences. 1. The onset of action is different: sildenafil usually takes effect between 0 and 2 hours, and is recommended to be taken 1 hour before sex. Vardenafil, on the other hand, can take effect in as little as 15 minutes in a fasted state, so it can be taken a little later. 2. Maintenance time is different: sildenafil is about 3~5 hours, vardenafil is about 5 hours, so the maintenance time of vardenafil is relatively longer. 3. The price is also different: in the current market, the price of sildenafil is cheaper, while vardenafil is more expensive. Need patients according to their own situation to specific choice, at the same time need to take under the guidance of the doctor, do not self-abuse of drugs, so as not to cause adverse effects.