Pain on both sides of lumbosacral region may be related to sacroiliac arthritis, herniated disc, lumbar muscle strain and other diseases. If the pain on both sides of the lumbosacral region is in the sacroiliac joint area, it may be caused by sacroiliac arthritis, such as ankylosing spondylitis encroaching on the sacroiliac joints, sacroiliac arthritis formed in the late stage of pregnancy when the sacroiliac joints are excessively stretched, and so on. If the pain on both sides of the lumbosacral spine is not located in the sacroiliac joint area, but the sacroiliac joint is lateralized, it may be caused by lumbar intervertebral disc herniation compressing the nerves. In addition to the pain on both sides of the lumbar spine, it will be accompanied by bilateral lower limb pain, numbness and other symptoms. The lumbar muscle is subjected to repeated pulling for a long time, and strain will occur, forming aseptic inflammation, which will also cause pain on both sides of the lumbosacral region. Once the lumbosacral pain on both sides, it is recommended that the patient go to the hospital in time for medical examination and targeted treatment after clarifying the cause of the disease.