Metformin, acarbose are oral hypoglycemic drugs, can not distinguish which hypoglycemic effect is the best, need to be based on the patient’s blood glucose elevation as well as the sensitivity of the drug and other aspects of the consideration, suitable for their own is better. 1. Metformin: for patients with type 2 diabetes, patients taking metformin can increase the sensitivity of peripheral tissues to insulin, improve insulin resistance, and then through the muscle uptake of glucose, so as to achieve the effect of lowering blood sugar. The common adverse reaction of metformin is gastrointestinal reaction, and it is forbidden for those who are allergic to it. 2. Acarbose: It is suitable for patients with type 2 diabetes mellitus, and mainly reduces postprandial blood glucose. The glucose-lowering mechanism of Acarbose is to inhibit the absorption of glucose in the intestines, and then achieve the purpose of lowering blood sugar. Some patients may have adverse reactions such as gastrointestinal flatulence and diarrhea after taking acarbose tablets, and it is prohibited for those who are allergic to it. Therefore, whether it is better to take Metformin or Acarbose should be judged by your doctor according to your own situation and combined with the doctor’s advice. At the same time, the medication should be used according to the doctor’s prescription, not self-medication.