Amoxicillin and cephalosporin belong to two different types of antibiotics, their effects are not good or bad, the appropriate is the best. Amoxicillin is a penicillin antibiotic used to treat infections caused by sensitive bacteria, such as otitis media, upper respiratory tract infections, genitourinary tract infections, skin and soft tissue infections. Its common adverse reactions include rash, diarrhea, nausea, etc. It is contraindicated for those who are allergic to penicillin as well as other β-lactam preparations. Cephalosporin is a large class of drugs that can be divided into five generations. Cefradine, for example, is a first-generation cephalosporin mainly used for acute pharyngitis, tonsillitis, otitis media, bronchitis, pyelonephritis caused by sensitive bacteria. Its adverse reactions include nausea, vomiting, diarrhea, etc. It is contraindicated for those who are allergic to cephalosporins and have a history of penicillin anaphylaxis. Please select the appropriate medication according to your condition under the guidance of your physician.