Brucellosis, also known as brucellosis, is a zoonotic infection that can be cured in most patients with early, adequate and full course of medication, and does not affect life expectancy. However, because the symptoms may be atypical after infection, sometimes it is not easy to diagnose, and if the disease does not receive timely and appropriate treatment, the survival period may be only six months to a year, or even a month to death. Early diagnosis of brucellosis can be combined with a history of exposure to domestic or wild animals, such as cattle, sheep, pigs, and deer, and timely standardized treatment can produce a significant improvement in the prognosis of this disease. The most important treatment option for brucellosis is antibiotic therapy, such as doxycycline combined with rifamycin, which is the preferred treatment for the acute and chronic stages of human brucellosis. The general course of treatment for 8 weeks, if the symptomatic diagnosis and treatment in a timely manner, and reasonable rest and recuperation, the prognosis is generally good, does not affect the life expectancy and no sequelae. If the acute phase is not treated in a timely manner and is not cured for more than one year, the disease may develop into chronic brucellosis. If it is not cured for a long time, it may be combined with other organs or tissue abscesses such as spondylitis, arthritis, etc. The treatment is relatively complicated and may require several treatments to cure. This condition, if cured, does not usually affect life expectancy, but there may be bone and joint sequelae, such as joint deformities. However, if the pathogen has invaded the nervous system and induced problems such as endocarditis, it may be life-threatening, and the specific survival time of the patient needs to be determined according to the development of the specific disease. During the treatment of brucellosis, patients need to pay attention to rest and supplementation. Due to the side effects of drugs such as doxycycline and rifampin, changes in blood routine, liver and kidney function need to be monitored during the use of drugs.