Tricuspid regurgitation may be induced by a variety of diseases, so the drugs taken are not fixed, such as commonly used diuretic drugs, vasodilator drugs, anticoagulant drugs, cardiotonic agents, etc., which need to be used according to the specific symptoms of the patient. 1. Diuretic drugs: such as furosemide, spironolactone, etc., can eliminate excess water in the body, reduce blood volume, used to reduce the burden on the patient’s heart, alleviate tricuspid regurgitation-induced edema, chest tightness and other symptoms. 2. Vasodilator drugs: such as enalapril, nitroglycerin, etc., can reduce blood pressure, improve coronary blood supply, can reduce pulmonary artery pressure, reduce tricuspid regurgitation, relieve pulmonary edema, chest tightness, chest pain. 3. Anticoagulants: such as aspirin, clopidogrel, etc., can reduce blood viscosity, improve myocardial blood supply, thus relieving chest tightness and chest pain caused by tricuspid regurgitation, and can also prevent thrombosis. 4. Cardiotonic agents: such as digoxin, sildenafil, etc., can increase the strength of ventricular contraction, promote the normal flow of blood from the ventricle to the atrium, thus reducing tricuspid regurgitation and relieving the symptoms of chest tightness and shortness of breath. All of the above drugs should be used under the guidance of a doctor. For mild tricuspid regurgitation without obvious symptoms, regular follow-up examinations can be conducted.