Whether or not to remove the gallbladder for 2cm gallstones is related to the location of the stone, clinical manifestations and other factors. Gallstones are categorized into gallbladder stones and bile duct stones according to the location of the stones. 1. Gallbladder stones: the typical symptom is biliary colic, which mostly occurs after eating greasy food. For symptomatic gallbladder stones or multiple 2cm gallbladder stones, laparoscopic cholecystectomy is the first choice; if asymptomatic and the number of stones is small, preventive surgical treatment is generally not required, and follow-up observation every 6 months is sufficient. 2. Bile duct stones: usually asymptomatic, when the stones cause bile duct obstruction secondary cholangitis, manifested as abdominal pain, chills and high fever and jaundice. Choledocholithiasis is preferred to choledochotomy + T-tube drainage, and cholecystectomy can be performed at the same time if accompanied by gallbladder stones and cholecystitis. If you find gallstones, you should be admitted to the hospital and follow the doctor’s advice.