The success of ovulation induction in premature ovarian failure is related to the degree of premature ovarian failure and sensitivity to ovulation induction drugs. In patients with premature ovarian failure, ovulation induction is usually not recommended because of the poor quality of the follicles. Patients need to use medication to regulate ovarian function, and after treatment, if the quality of follicles growing in the ovaries will gradually improve, ovulation can be promoted. Patients with premature ovarian failure will have ovulation disorder, this time the ovary will lose normal function, and patients may be accompanied by amenorrhea and menstrual scanty phenomena, so if the ovarian function decline leads to poor follicle quality, ovulation will not be good, so it is not recommended to promote ovulation treatment, it is recommended to symptomatic conditioning of the ovarian function first. Patients with premature ovarian failure need to develop regular living habits, to maintain a relaxed mood, to avoid excessive mental stress. Whether patients with premature ovarian failure can be treated with ovulation induction therapy needs to be judged according to the patient’s physical condition, and it is necessary to follow the doctor’s instructions.