The following diseases are clinically associated with painful throat pressure, each with a different treatment approach. The first, which is the most common, is acute inflammatory infection of the pharynx. The common ones are acute pharyngitis, acute purulent tonsillitis, peri-tonsillitis, acute epiglottitis, etc. Inflammation involving the soft tissues of the neck and the interstitial space can cause painful pressure on the neck. Inflammation of the lymph nodes in the neck may also cause pain. In this case, the main clinical treatment is anti-inflammatory treatment with adequate antibiotics and, if necessary, symptomatic treatment with hormones. Second, the disease is that some patients have a history of neck trauma, such as neck bruises, pinch injuries resulting in some cartilage dislocation or fractures in the neck, in this case, pressure will appear pain. If the fracture is not obvious, it can be treated conservatively; if the fracture is obvious, it can be treated by surgical repositioning. Third, some patients have inflammatory diseases of the thyroid gland, commonly subacute thyroiditis, which is manifested by tenderness in the thyroid area of the neck. In this case, it is usually necessary to improve the thyroid ultrasound, the eight items of thyroid function and other related examinations, and it is also recommended that the patient go to the endocrinology department for hormone and other comprehensive treatment. Fourthly, some patients have carotid arteritis, which is a non-infectious inflammation of the carotid sheath. Clinically, pain medication can be given for short-term treatment.