Coronaviruses can certainly mutate, mainly due to their biological and genetic properties. The coronavirus is a nucleic acid virus synthesized by RNA, which is characterized by a single-stranded nucleic acid forming a gene chain that is particularly prone to mutation, and its protein phenotype will change after mutation, as many animals appear to be close relatives, including many viruses that have many different subtypes, such as influenza. It will have H5N1, H5N7, H7N9 and so on, which are due to the nucleic acid mutation after the protein phenotype also changed. So the coronavirus has been found to have mutated this situation, the future may be for the prevention and control of new coronavirus is a long way to go, and will provide very difficult.