High platelet distribution width means that the platelet size disparity, which may suggest acute myeloid leukemia, megaloblastic anemia and other diseases, the specific need to be combined with other indicators to determine, it is recommended to consult a doctor in a timely manner. Platelet distribution width mainly reflects the degree of platelet size dispersion, that is, the degree of platelet volume size difference in the peripheral blood, the normal value is within the range of 15% to 17%, the index increased, indicating that the platelet volume size difference in the peripheral blood is large. This abnormality is usually seen in acute myeloid leukemia, megaloblastic anemia, splenectomy, giant platelet syndrome, and thrombophilia. It is difficult to make an accurate diagnosis based only on this one index abnormality. It is recommended to go to the hospital in time, and the physician will combine other indicators (such as platelet count) to make a diagnosis.