Erythrocyte homogeneity with proteinuria may be due to physiological factors such as strenuous exercise or pathological factors such as urinary tract stones, urinary tract infections, urinary tract tumors, systemic diseases. 1. Physiological factors: urine erythrocyte homogeneity with proteinuria can be seen after strenuous exercise, female menstrual period specimen contamination, high protein diet and other physiological conditions, usually do not need special treatment, after the removal of the causative factors can return to normal. 2. Pathologic factors: (1) urinary tract stones: can be seen in ureteral stones and kidney stones and other urinary tract stone diseases, usually easy to cause symptoms of urinary red blood cells and urinary protein. (2) Urinary tract infection: due to pathogenic microbial infection leading to acute pyelonephritis, urinary tract infection and other infections of the urinary tract, can be due to inflammation stimulation of the local mucous membrane, leading to mucous membrane rupture edema, which leads to erythrocytes and proteins enter into the urine phenomenon, resulting in red blood cells and proteins in the urine, and so on. (3) Tumor of urinary tract: it can be seen in kidney tumor, bladder tumor and other tumors of urinary tract, which can lead to capillary rupture and bleeding, thus causing hematuria and proteinuria and other symptoms. (4) Systemic diseases: it can also be seen in thrombocytopenic purpura, hemophilia and other systemic diseases, which can cause renal injury, thus leading to red blood cells and protein in urine. If the discovery of hematuria and proteinuria and other discomforts, it is recommended that patients go to the hospital in a timely manner, follow the doctor’s instructions to improve the relevant examination, under the guidance of the doctor standardized diagnosis and treatment.