Cramps, also known as muscle spasms, physiological factors lead to no medication, pathological factors lead to, according to the specific cause of the selection of the appropriate drug treatment, such as calcium, diazepam, phenytoin sodium, etc.. 1. Physiological factors: generally due to cold stimulation, excessive fatigue and other reasons, should pay attention to keep warm, pay attention to avoid strenuous exercise, warm up before exercise, etc., without drug treatment. 2. Cramps caused by pathological factors need to be treated for the cause. (1) Hypocalcemia: If the cramps are caused by hypocalcemia, calcium supplementation should be given, such as calcium carbonate, calcium gluconate, etc., and more calcium-containing foods, such as milk, should be eaten. (2) Febrile convulsions: children with convulsions due to high fever can also lead to muscle spasms, diazepam should be given symptomatic treatment, the cause of high fever needs to be further clarified, and the treatment should be directed at the primary disease. (3) Epilepsy: muscle spasms can occur during seizures, preferred antiepileptic drugs such as phenytoin sodium and sodium valproate. The appearance of cramps if the disease is caused, should actively seek medical attention, under the guidance of the doctor for treatment.