Coughing up green sputum may be caused by respiratory tract infectious diseases or sinusitis, and antibiotic treatment should be given according to different diseases. 1. Respiratory tract infectious diseases: such as bronchial dilatation patients can often be manifested as coughing green sputum, mostly considered to be caused by Pseudomonas aeruginosa infection. Treatment is based on anti-infection. Treatment, can be empirically selected cefixime, moxifloxacin and other antibiotics, if necessary, according to the drug sensitivity test to select the most suitable antibiotics for treatment. 2. Sinusitis: Sinusitis with bacterial infection, such as streptococcus, Pseudomonas aeruginosa infection can appear green nasal discharge, such as nasal discharge back into the mouth, can appear cough green sputum. Treatment can be anti-infective treatment with antibiotics such as roxithromycin, amoxicillin and cefixime. In addition to this, there are other diseases that can also cause green sputum to be coughed up. If the symptoms are not relieved or aggravated, it is recommended to go to the hospital for a relevant examination, under the guidance of specialists to clarify the cause of the disease, and follow the doctor’s instructions to use medication.