Excessive duodenal drainage may be caused by infection, anastomotic obstruction, etc. It can be relieved by anti-infective treatment and surgical treatment. 1. Infection: when patients need to place a drain after duodenal surgery, when an infection occurs, it will lead to an increase in local exudation and make the drainage fluid excessive. At this time, patients can use drugs such as: cefixime, ceftriaxone and other drugs under the guidance of the doctor for anti-infection treatment, which can play a very good role. 2. Anastomotic obstruction: when the duodenal anastomosis is blocked, the liquid in the intestinal lumen can not be discharged downward, which will lead to excessive drainage fluid in the drainage tube, and then the incision can be surgically reanastomosed to make the intestinal tube unobstructed again. Patients with excessive duodenal drainage need to explain the situation to their doctor in time to identify the cause and treat it.