Deep multiple demyelinating changes in the white matter of the brain may or may not be serious, mostly seen in multiple sclerosis, acute disseminated encephalomyelitis, cerebral white matter dystrophy, etc., which need to be determined in conjunction with the specific disease and its degree.
1. Multiple sclerosis: The prognosis of most multiple sclerosis patients is optimistic, about half of the patients only have mild or moderate dysfunction left 10 years after the onset of the disease, and the survival period after the disease can be as long as 20-30 years, but a few patients can die within a few years.
2. Acute disseminated encephalomyelitis: the prognosis is related to the cause of the disease and the severity of the disease, and most patients can recover. The mortality rate is reported to be 5%~30%. Survivors often have obvious functional disabilities, and children often have mental retardation or seizures after recovery.
3. Cerebral leukodystrophy: a group of myelin formation defects due to genetic factors, including heterotrophic cerebral leukodystrophy, adrenoleukodystrophy, etc., which is common in children, with extensive neurological involvement, poor prognosis and high mortality.
4. Other diseases: diffuse sclerosis has a poor prognosis, progressive deterioration after the onset of most patients die in a few months to a few years, the cause of death is mostly due to co-infection. Most patients can recover from concentric sclerosis, and some patients die from complications. Progressive multifocal leukoencephalopathy usually lasts several months and 80% of patients die within 9 months.
There are other causes of deep multifocal demyelinating changes in the white matter of the brain, such as, for example, delayed leukoencephalopathy after carbon monoxide poisoning, neurosyphilis, and subacute sclerosing total encephalitis. The prognosis is variable.
Prompt medical attention is recommended to identify the cause and treat it.