Loratadine tablets can only be taken once a day, one tablet at a time. If the patient is hepatic insufficiency, it is recommended to take it every other day. The medication can also be taken with food or on an empty stomach, but if stomach discomfort occurs, take it with food. The medication can be taken in the morning to control allergy symptoms during the day, or before bedtime if the symptoms occur mostly at night. The medication can affect the results of skin allergy tests, such as penicillin skin tests, so it is best to stop taking the medication forty-eight hours before the skin test. Side effects such as fatigue, headache, drowsiness, dry mouth, nausea, etc. may occur with loratadine, and it must be taken continuously and regularly to completely control the symptoms and heal before stopping the drug, because oral antihistamines need to be absorbed through the intestinal tract and need to reach a certain blood concentration to be effective. Therefore, you should use the medication before the symptoms appear, avoid taking the medication on demand, and follow the medical advice to take the medication according to the course of treatment.