In patients with constipation, the stool is too dry and hard, which may cause the anus to tear during defecation, in which case the patient will experience more intense pain and bleeding. The first step in treatment is to target constipation by drinking more water, eating more vegetables and fruits, and increasing fiber intake. If constipation is not relieved after improving lifestyle, you can take oral medications that soften stools and increase stool moisture, including bulking laxatives such as polyethylene glycol and methylcellulose, and osmotic laxatives such as lactulose, supplemented with medications that help intestinal peristalsis, such as mosapride and itopride. For pain caused by anal fissures you can use topical hemorrhoid cream, lidocaine cream application, which can reduce the pain sensation to some extent.