When cancer reaches the advanced stage, metastasis to other sites may occur, and the sites to which the metastasis occurs are also an important influencing factor in determining the subsequent survival period. For example, if the metastasis is only to the peripheral lymph nodes, it is possible that the treatment effect will be better through localized treatment, including radiotherapy and systemic chemotherapy and targeted therapy, which will not affect the life expectancy for the time being, and of course, the primary cancer lesion will have to be seen to see if there is any further development. If the cancer has metastasized to vital organs, such as liver metastasis, lung metastasis, brain metastasis, etc., it may lead to vital organ failure, which in turn leads to a short life expectancy, which may be from half a year to one year, or it may have a better effect, exceeding one year, two years, and a longer period of time. Each patient is different and can only be treated and seen. In some cases, there are bone metastases, which are not vital organ metastases, and as long as there are no pathologic fractures, the patient may have a longer survival time.