Cefixime in children may cause allergic reactions, gastrointestinal reactions, and cause dysbiosis. 1. Allergic reaction: there is a possibility of allergy to cefixime, especially in children who are allergic to penicillin, and cross infection may occur. So children must pay attention to whether there are signs of allergy when taking Cefixime. 2. Gastrointestinal reaction: Cefixime affects the gastrointestinal tract of children, and nausea and vomiting, diarrhea, and abdominal discomfort may occur. 3. Causes dysbiosis: Cefixime is a third-generation cephalosporin antibiotic. It kills pathogenic bacteria as well as beneficial bacteria in the intestinal tract, thus causing intestinal flora imbalance. When children take Cefixime, if any discomfort occurs, they should immediately go to the hospital for consultation and treatment under the guidance of a professional doctor.