The diagnosis of Kawasaki disease low blood pressure is mainly due to vascular inflammation, mainly through the control of immune-inflammatory reaction and anti-platelet treatment. 1. Control immune inflammatory response: can follow the medical advice to use glucocorticoid drugs, such as hydrocortisone tablets, dexamethasone tablets, this kind of drugs can effectively inhibit and eliminate the inflammatory response, suitable for children with more serious diseases, the drug can promote thrombosis, prone to coronary artery aneurysm and affect the repair of coronary artery lesions, so it can not be applied alone, can be used in conjunction with aspirin, bispyrimidine, and improve the problem of low blood pressure. And then improve the problem of low blood pressure. 2. Antiplatelet: When Kawasaki disease is combined with coronary artery damage and huge coronary artery aneurysm, it is necessary to prevent thrombosis, and thrombolytic therapy should be carried out after thrombosis is formed, including the application of urokinase, heparin, low molecular heparin and heparin sodium, etc. to carry out thrombolytic therapy, which can improve the problem of low blood pressure. If a patient is diagnosed with Kawasaki disease with low blood pressure, it is recommended to consult a doctor in time and take active treatment to avoid further aggravation of the condition.