More than two weeks after the chemotherapy of acute myeloid leukemia M2, there is a high platelet index, need to be treated according to the cause of the disease, generally common causes are hormones, blood concentration, infection and hematopoietic recovery, etc., and the methods adopted include observation, strengthening nutrition and controlling infection. 1. Hormone: the use of hormone drugs, such as glucocorticoids, in the course of M2 chemotherapy for acute myeloid leukemia may lead to the phenomenon of high platelets, and generally given to the observation and treatment, with the prolongation of time, platelets may gradually decline. 2. Concentration of blood: After chemotherapy, appetite may decrease, which will reduce the water in the blood and require concentration of blood, and the platelet count will be high. Generally, nutrition should be strengthened, and light and easy-to-digest diets should be consumed as much as possible. 3. Infection: due to the weakened body after chemotherapy, infection may occur, infection may lead to the phenomenon of high platelet count, should go to the hospital to control the infection in time. 4. Hematopoietic recovery: Because the normal hematopoiesis of bone marrow is inhibited at the onset of the disease, when the disease is in complete remission and the bone marrow suppression period is over, the hematopoiesis of bone marrow may show transient enhancement of function and transient thrombocytosis, which can be monitored regularly. If platelets are high more than two weeks after M2 chemotherapy for acute myeloid leukemia, you should go to a regular hospital in time, and the doctor will judge the cause according to the specific condition, and give you the correct treatment for the cause of the disease.