Gastrointestinal dysfunction with significant weight loss is considered to be caused by indigestion and impaired absorption of food. It is recommended to improve the symptoms of gastrointestinal dysfunction first: on the one hand, through dietary regulation, try to eat light, easily digestible food, such as millet porridge and other foods, while eating more vegetables and fruits to increase the intake of various vitamins and trace elements, long-term use of antibiotic drugs to avoid damage to the intestinal flora. At the same time, you can take drugs to regulate the intestinal flora to further improve the intestinal flora. On the other hand, you can also take Chinese medicine to strengthen the spleen and stomach, such as Jianshuanyuan and Guixianwan, to regulate the function of the spleen and stomach to enhance the absorption and digestion of food. If necessary, gastroscopy can be performed to check whether there are multiple local polyps and mucosal damage.