The duration of Metformin Hydrochloride tablets is generally recommended to be taken with meals and should be used as prescribed by the doctor, starting with small doses and gradually increasing the dose according to the condition. Metformin hydrochloride is an oral hypoglycemic drug, which exerts its hypoglycemic effect by inhibiting hepatic glucose output and increasing insulin sensitivity, and is suitable for type 2 diabetes. It is recommended to take it with meals, or if you are afraid of forgetting, you can choose to take it with the first bite of your meal. The common side effects of this drug are nausea, vomiting, abdominal pain, and diarrhea. Therefore, it is advisable to start with a small dose for the first time and gradually increase the dose according to the patient’s digestive tract tolerance as prescribed by the doctor. If a higher dose is prescribed, it is best to take the drug in divided doses with three meals for better tolerance. In addition, Metformin Hydrochloride Tablets should not be used in patients with acute complications of diabetes and severe renal insufficiency, and should be used with caution in consultation with an endocrinologist. Metformin can reduce the absorption of vitamin B12, long-term use of metformin, you can properly supplement vitamin B12.