1. One thing that is confusing: for patients, taking medication after thyroid papillary cancer surgery is a very important and critical treatment, but it is another thing that confuses patients. Endocrinologists often disrupt the treatment given to patients by oncologists. As soon as they see abnormal thyroid function, they seriously and seriously tell patients: You must reduce the dosage or even ask to stop the medication. When they return to the main surgeon, they ask to increase the dosage again. Even among thyroid cancer specialists, there are many arguments about taking medication, or rather, there is no unified understanding of taking medication after thyroid papillary cancer surgery itself. 2.What kind of medication should I take after thyroid cancer surgery? The most commonly used one is levothyroxine sodium tablets (eugenol). 3. How to take thyroxine tablets? Thyroxine tablets should be taken in the morning on an empty stomach after waking up, and you can eat after taking the medicine. The starting dosage and the adjustment of dosage must follow the specialist’s advice, as a small dosage cannot achieve the treatment purpose. A small amount of medication will not achieve the therapeutic purpose. A large amount of medication will cause side effects. 4. What are the side effects after taking the medication? A. For patients with little residual thyroid gland, a small amount of medication and insufficient thyroid function can cause symptoms of hypothyroidism: according to the severity of clinical manifestations, there are four stages. (1), subclinical stage That is, the initial insidious stage, which may have no clinical manifestations. The main diagnostic basis of this stage is a mild increase in TSH. (2) Clinical hypothyroidism stage can be divided into light and heavy. The former has mild or atypical symptoms, showing only non-specific symptoms such as weakness, drowsiness, loss of appetite, and a feeling of peripheral swelling; while the latter has a light mucinous edema-like manifestation. (3) The early symptoms of mucinous edema stage start from the 4th week, and the typical symptoms are common after the 8th week. B. Taking too much medication can lead to hyperthyroidism: 1), accelerated metabolism: Patients taking levothyroxine sodium tablets just after surgery may experience an increase in meal size. This is because the supplemental thyroxine speeds up the body’s metabolism and can lead to a condition of weight gain or loss: eating too much and not being able to consume it will of course make you fat; eating more but metabolizing it more quickly makes you thin. (2), drug hyperthyroidism: Patients will also have some symptoms of hyperthyroidism, such as excessive sweating, dryness, high mood swings, anxiety, frequent hunger, weight loss, rapid heartbeat, panic and shortness of breath, which are manifestations of drug hyperthyroidism. These symptoms need to be reviewed for thyroid function and medication dose adjustment. C. Other: Patients may also develop osteoporosis, liver function damage, and menstrual disorders in female patients, which require symptomatic treatment. Liver function impairment can be treated with liver-protective drugs, and osteoporosis needs to be regulated with calcium tablets. Thyroid hormone has a certain influence on the ovarian function and menstrual regulation of women, so female patients may have prolonged menstrual cycle, amenorrhea and other symptoms, at this time to adjust the amount of medication, so that the normal level of thyroid hormone, menstruation will naturally improve. 5, how to review and adjust after taking medication: taking thyroxine medication, the effect on the blood needs more than 2 weeks, so their own point of view: patients are generally required to review the thyroid function 1 month after taking medication, and then every 3 months, two consecutive times to achieve the requirements of the drug, on half a year to a year to review can be. For patients who do not meet the requirements and need to adjust their medication, thyroid function should be rechecked after one month from the date of medication adjustment. For the effect of osteoporosis and liver function, it is required to check once every two years. As there is no unified standard for post-operative medication, the standard recommended by the American Thyroid Association is complex and difficult to be copied completely in China (biochemical examination is carried out by very few units in China). is required to be controlled below 0.1 mU/L B. For patients with complete surgical resection, it is sufficient to control TSH at a level slightly lower than normal (TSH < 0.27 mU/L: TSH monitoring standard at Peking University Cancer Hospital, different equipment). It is not necessary to require the TSH to reach a fixed value, because the human body changes every moment, the same dose of thyroxine, corresponding to the TSH will have great fluctuations, and it is impossible to control the TSH at a fixed level. C. Take the medicine for 5 years, check the tumor without recurrence, and can control TSH at normal level. If the patient has enough thyroid tissue remaining, the drug can even be stopped completely.